Protein name:
Growth arrest-specific protein 6 (GAS-6) ;
Alternative:
AXL receptor tyrosine kinase ligand ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Heterodimer and heterotetramer with AXL.
Function:
Ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, platelet activation, or regulation of thrombotic responses.
Subcellular Location:
Secreted
Protein Attributes:
50:
MPPPPGPAAA | LGTALLLLLL | ASESSHTVLL | RAREAAQFLR | PRQRRAYQVF |
100:
EEAKQGHLER | ECVEEVCSKE | EAREVFENDP | ETEYFYPRYQ | ECMRKYGRPE |
150:
EKNPDFAKCV | QNLPDQCTPN | PCDKKGTHIC | QDLMGNFFCV | CTDGWGGRLC |
200:
DKDVNECVQK | NGGCSQVCHN | KPGSFQCACH | SGFSLASDGQ | TCQDIDECTD |
250:
SDTCGDARCK | NLPGSYSCLC | DEGYTYSSKE | KTCQDVDECQ | QDRCEQTCVN |
300:
SPGSYTCHCD | GRGGLKLSPD | MDTCEDILPC | VPFSMAKSVK | SLYLGRMFSG |
350:
TPVIRLRFKR | LQPTRLLAEF | DFRTFDPEGV | LFFAGGRSDS | TWIVLGLRAG |
400:
RLELQLRYNG | VGRITSSGPT | INHGMWQTIS | VEELERNLVI | KVNKDAVMKI |
450:
AVAGELFQLE | RGLYHLNLTV | GGIPFKESEL | VQPINPRLDG | CMRSWNWLNG |
500:
EDSAIQETVK | ANTKMQCFSV | TERGSFFPGN | GFATYRLNYT | RTSLDVGTET |
550:
TWEVKVVARI | RPATDTGVLL | ALVGDDDVVP | ISVALVDYHS | TKKLKKQLVV |
600:
LAVEDVALAL | MEIKVCDSQE | HTVTVSLREG | EATLEVDGTK | GQSEVSTAQL |
650:
QERLDTLKTH | LQGSVHTYVG | GLPEVSVISA | PVTAFYRGCM | TLEVNGKILD |
674:
LDTASYKHSD | ITSHSCPPVE | HATP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Mouse GAS-6
ELISA Kit for Mouse GAS-6
ELISA Kit for Mouse GAS-6
Polyclonal Antibody for Mouse GAS-6
Polyclonal Antibody for Mouse GAS-6
Polyclonal Antibody for Mouse GAS-6
Monoclonal Antibody for Mouse GAS-6
Monoclonal Antibody for Mouse GAS-6
Monoclonal Antibody for Mouse GAS-6
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Recovery
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.
"Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis."
Angelillo-Scherrer A.
,
de Frutos P.
,
Aparicio C.
,
Melis E.
,
Savi P.
,
Lupu F.
,
Arnout J.
,
Dewerchin M.
,
Hoylaerts M.
,
Herbert J.
,
Collen D.
,
Dahlback B.
,
Carmeliet P.
Nat. Med.7:215-221(2001)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION